Repent, for the kingdom of heaven is at hand.

Everyone's personal problem is clearly defined in God's word:

Romans 3:10 As it is written, There is none righteous, no, not one: 11 There is none that understandeth, there is none that seeketh after God. 12 They are all gone out of the way, they are together become unprofitable; there is none that doeth good, no, not one.

Everyone's one hope is declared in God's word:

John 3:36 He that believeth on the Son hath everlasting life: and he that believeth not the Son shall not see life; but the wrath of God abideth on him.

Jesus' sacrifice of Himself is the only sacrifice which God accepts as expiation of our sins:

Hebrews 10:12 But this man, after he had offered one sacrifice for sins for ever, sat down on the right hand of God;